Day Trips & Multi-Day Tours from Mesopotamia, Ohio

Swap Ohio for Appalachian pines and theater lights on this five-day Ridgeview Country Tours trip to Gatlinburg. Experience Dollywood’s holiday displays, three dinner shows, a guided Smokies tour, the Titanic Museum, Ole Smoky tasting, and holiday shopping.

Spend a day on Lake Erie and in Cleveland’s Westside Market: a narrated two-hour cruise aboard the Lady Caroline, a walk through Cleveland’s oldest public market, a one-hour guided Ohio City tour, and a Mitchel’s Homemade Ice Cream cone to finish. This is a compact, flavorful introduction to Cleveland’s lakefront and food scene.

Two days of live theater, Pennsylvania Dutch flavor and one unforgettable smorgasbord—this weekend package pairs All Shook Up at Dutch Apple with the biblical spectacle JOSHUA at Sight & Sound. Stay at Bird-In-Hand Family Inn and savor a Shady Maple meal while a guided Lancaster tour fills the gaps.

Two days of river cruising, local history, and a guided tour of an 18th-century Palladian mansion. Board the Valley Gem Sternwheeler, explore downtown Marietta, and spend a day on Blennerhassett Island State Park.

Spend a full day tasting and shopping through Ohio’s Amish Country—cheese-making demos, a home-style buffet, a massive fresh-food market, and a winery tasting all rolled into one guided motorcoach tour. Perfect for food lovers who want local flavor without the drive.

Spend a day off the interstate exploring Sugar Creek’s live theater, Amish lunch, and the expansive Walnut Creek Cheese market. This Ridgeview Tours outing bundles local performance, shopping, and hearty food into an easy, full-day experience.

Cross two states in one festive day: stroll through downtown Steubenville’s record-setting life-size nutcracker display, then roll through Oglebay Park’s million-light Festival of Lights. This easy bus tour is perfect for families and anyone who wants high-impact holiday sights without the driving.

Spend a day in Jamestown exploring Lucille Ball’s hometown: guided museum access, a Tropicana Club lunch, and a motorcoach tour of murals, homes, and a statue that celebrate TV’s most famous redhead. This single-day itinerary packs history, photo ops, and easy walking into a nostalgic, well-paced outing.

Spend a crisp autumn day tracing rails, history and candy across the Alleghenies. Ride Amtrak’s Pennsylvanian, explore the Railroaders Memorial Museum and savor a hearty buffet while trees blaze in fall color.

A full-day shuttle takes you from Ravenna or Niles to Mountaineer Casino & Horse Racing on the Ohio River — over 1,000 slots, live thoroughbred racing, and river views. Perfect for a day of gaming, racing culture, and easy transport back home.

Celebrate America’s 250th with a three-day road trip to Dearborn: factory tours, the Henry Ford Museum, Greenfield Village, pottery-making, and presidential history. This all-inclusive bus tour pairs immersive exhibits with hands-on moments for travelers who love machines and stories.

Spend a day traveling from Mesopotamia, Ohio, to Frank Lloyd Wright Falling Waters and the Quecreek Mine Rescue site: architecture, a waterfall walk, a hearty lunch at Brandy’s, and firsthand rescue history all in one trip. Ideal for travelers who want design, landscape, and regional history in a single outing.

Step aboard a one‑day bus tour from Mesopotamia to explore the JE Reeves Victorian Mansion in Dover and the Dickens Victorian Village in Cambridge. This paired experience blends period interiors, street‑level theater, and a included group dinner—perfect for seasonal outings in November and December.