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14-Day Road Trip Across Northwest Argentina: Route 40, Salinas Grandes & Quebradas - Salta

14-Day Road Trip Across Northwest Argentina: Route 40, Salinas Grandes & Quebradas

Saltamoderate

Difficulty

moderate

Duration

14 days

Fitness Level

Moderate fitness for several short hikes and the stamina to sit through multiple 4–6 hour driving legs; ability to walk on uneven terrain at altitude.

Overview

Follow Route 40 across northern Argentina on a 14-day road trip that moves from Córdoba’s green valleys to the high‑altitude salt flats, volcanic valleys and color-splashed canyons of Salta and Jujuy. Expect long drives, short hikes, local wine, and dramatic altitudinal shifts that reward careful pacing.

14-Day Road Trip Across Northwest Argentina: Route 40, Salinas Grandes & Quebradas

Jeep
Bus Tour
Sightseeing Tour

The road bends and a new color takes over: ochre canyons give way to white salt flats, and the wind carries the dry, cold air of the high Andes. You’re driving Route 40, and the vehicle’s hum becomes a metronome for a country of extremes — Pampas plains, cactus forests, volcanic moonscapes and villages where time moves on its own schedule.

Adventure Photos

14-Day Road Trip Across Northwest Argentina: Route 40, Salinas Grandes & Quebradas photo 1

Adventure Tips

Acclimatize before high passes

Spend a night or two at 1,500–1,700 m (Cafayate/Salta) before ascending above 3,000 m to reduce altitude sickness risk.

Carry cash for remote stops

Small villages and roadside vendors often accept only cash—keep local pesos for snacks, tips and market purchases.

Protect against sun and wind

High-altitude UV and desert wind are strong—use SPF 50+, a wide-brim hat and windproof outer layer.

Expect varied road surfaces

Some stretches require a 4x4 and include gravel or sand; flexible timing and closed footwear help when leaving paved routes.

Local Insights

Wildlife

  • Andean flamingos
  • Free‑roaming llamas and vicuñas

History

The route crosses ancient indigenous territories including sites linked to the Quilmes culture; many towns retain 300‑year colonial layouts and architecture.

Conservation

High‑altitude ecosystems are fragile — stick to trails on salt flats and pumice fields, avoid collecting geological samples, and minimize plastic waste.

Adventure Hotspots in Salta

Frequently Asked Questions

Recommended Gear

Daypack (20–30L)

Essential

Keeps water, layers and camera handy during short hikes and village walks.

Sturdy hiking boots

Essential

Provides support on rocky trails, pumice fields and unpaved village paths.

High-SPF sunscreen & wide-brim hat

Essential

Vital protection from intense high-altitude UV and desert sun.

summer specific

Insulating layers and windproof jacket

Essential

Cold nights and windy passes require warm, packable layers.

winter specific