Follow Route 40 across northern Argentina on a 14-day road trip that moves from Córdoba’s green valleys to the high‑altitude salt flats, volcanic valleys and color-splashed canyons of Salta and Jujuy. Expect long drives, short hikes, local wine, and dramatic altitudinal shifts that reward careful pacing.
More ways to explore the area's outdoor wonders
The road bends and a new color takes over: ochre canyons give way to white salt flats, and the wind carries the dry, cold air of the high Andes. You’re driving Route 40, and the vehicle’s hum becomes a metronome for a country of extremes — Pampas plains, cactus forests, volcanic moonscapes and villages where time moves on its own schedule.
Difficulty
moderate
Duration
14 days
Fitness Level
Moderate fitness for several short hikes and the stamina to sit through multiple 4–6 hour driving legs; ability to walk on uneven terrain at altitude.
Wildlife
History
The route crosses ancient indigenous territories including sites linked to the Quilmes culture; many towns retain 300‑year colonial layouts and architecture.
Conservation
High‑altitude ecosystems are fragile — stick to trails on salt flats and pumice fields, avoid collecting geological samples, and minimize plastic waste.
Reserve your spot on the Road Trip Adventure Across North West Argentina today and enjoy a trusted, highly rated experience designed to help you make the most of your adventure.
Acclimatize before high passes
Spend a night or two at 1,500–1,700 m (Cafayate/Salta) before ascending above 3,000 m to reduce altitude sickness risk.
Carry cash for remote stops
Small villages and roadside vendors often accept only cash—keep local pesos for snacks, tips and market purchases.
Protect against sun and wind
High-altitude UV and desert wind are strong—use SPF 50+, a wide-brim hat and windproof outer layer.
Expect varied road surfaces
Some stretches require a 4x4 and include gravel or sand; flexible timing and closed footwear help when leaving paved routes.
Daypack (20–30L)
Keeps water, layers and camera handy during short hikes and village walks.
Sturdy hiking boots
Provides support on rocky trails, pumice fields and unpaved village paths.
High-SPF sunscreen & wide-brim hat
Vital protection from intense high-altitude UV and desert sun.
summer
Insulating layers and windproof jacket
Cold nights and windy passes require warm, packable layers.
winter