Begin your Peru trip gently in Arequipa and build altitude gradually through Colca, Puno and Cusco before visiting Machu Picchu. This 10-day itinerary mixes geology, colonial architecture and living Andean culture with practical pacing for acclimatization.
More ways to explore the area's outdoor wonders
You step off the plane into Arequipa at roughly 2,335 m and the air feels clean and thin; white volcanic rock buildings catch the light while Misti and Chachani stand motionless on the horizon. The city’s plazas and narrow streets are an easy first day of movement, the kind of slow approach that protects your lungs for higher passes to come.
Difficulty
moderate
Duration
10 days
Fitness Level
Moderate fitness recommended — able to handle multiple hours of walking, stairs and long vehicle transfers at high altitude.
Wildlife
History
Arequipa’s colonial core is largely built from sillar, a white volcanic stone; the route links colonial-era towns with Inca-period terraces and pre-Inca mortuary sites like Sillustani.
Conservation
Support community-run enterprises and avoid single-use plastics; stay on marked paths, don’t feed wildlife and buy artisan goods directly from local families to keep benefits in the communities.
Reserve your spot on the Perú tour in 10 days starting upon arrival to Arequipa quiet city today and enjoy a trusted, highly rated experience designed to help you make the most of your adventure.
Prioritize acclimatization
Spend the first day in Arequipa and avoid sudden exertion; the itinerary reaches passes near 4,900 m where symptoms can appear.
Bring cash for local fees
Small entrance fees, tips and snack purchases are often cash-only in mountain villages and islands like Taquile and Uros.
Sun and cold protection
High-altitude sun is intense while mornings and nights are cold—pack SPF 50, a brimmed hat and an insulating mid-layer.
Plan for long travel days
Several days include multi-hour drives or bus transfers (including a night bus to Cusco); bring a neck pillow, snacks and motion-sickness remedies.
Insulating mid-layer (fleece/down)
Warm mornings and nights in the high Andes make a good mid-layer essential.
Waterproof shell jacket
Rain or wind can appear suddenly above 3,000 m — a lightweight shell keeps you dry and warm.
Sturdy hiking shoes
Trails to ruins and island paths are uneven; supportive, broken-in footwear helps prevent blisters.
Reusable water bottle with purifier/filters
Hydration is critical at altitude and some stops have limited potable water options.